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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC1A
All Species:
23.33
Human Site:
S176
Identified Species:
36.67
UniProt:
Q5VZY2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VZY2
NP_001025230.1
271
30395
S176
T
E
S
G
R
G
K
S
W
R
L
C
A
A
I
Chimpanzee
Pan troglodytes
XP_001170623
223
25141
K129
A
S
F
Y
L
A
G
K
L
H
C
F
T
P
Q
Rhesus Macaque
Macaca mulatta
XP_001092746
343
37863
F235
S
G
H
S
S
F
A
F
A
G
L
A
F
A
S
Dog
Lupus familis
XP_535038
333
36609
S238
T
E
S
G
R
G
K
S
W
R
L
C
A
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBU9
271
30425
S176
T
E
S
G
R
G
K
S
W
R
L
C
A
A
I
Rat
Rattus norvegicus
O08564
282
31978
F174
F
Y
S
G
H
S
S
F
S
M
Y
C
M
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514919
461
51675
S182
T
E
N
G
R
G
R
S
W
R
L
C
A
A
I
Chicken
Gallus gallus
XP_426544
322
36285
S227
T
E
N
G
R
G
K
S
W
R
L
C
A
A
I
Frog
Xenopus laevis
Q6GQ62
226
25153
C132
Y
L
A
G
K
L
R
C
F
S
P
C
G
R
G
Zebra Danio
Brachydanio rerio
XP_002664129
282
31516
S183
T
D
A
G
R
G
R
S
W
R
L
C
A
M
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623887
268
30640
H173
L
Y
I
A
G
K
L
H
T
F
S
L
G
K
G
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
P227
L
N
N
R
I
V
V
P
I
S
Q
T
L
M
F
Sea Urchin
Strong. purpuratus
XP_787511
258
29394
G163
E
S
R
G
R
G
V
G
W
R
I
L
V
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
V195
V
F
D
Q
R
G
H
V
A
K
L
C
I
V
I
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
S192
C
G
Q
L
L
T
E
S
P
L
M
P
L
W
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
48
77.7
N.A.
99.2
25.5
N.A.
48.1
77.3
52.4
71.2
N.A.
N.A.
47.9
24.3
46.1
Protein Similarity:
100
64.9
60
79.8
N.A.
99.2
41.1
N.A.
53.3
80.4
63.4
83.6
N.A.
N.A.
66.7
39.8
64.2
P-Site Identity:
100
0
13.3
100
N.A.
100
20
N.A.
86.6
93.3
13.3
66.6
N.A.
N.A.
0
0
33.3
P-Site Similarity:
100
0
20
100
N.A.
100
20
N.A.
100
100
40
93.3
N.A.
N.A.
0
6.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.4
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
14
7
0
7
7
0
14
0
0
7
40
40
0
% A
% Cys:
7
0
0
0
0
0
0
7
0
0
7
60
0
0
0
% C
% Asp:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
34
0
0
0
0
7
0
0
0
0
0
0
0
0
% E
% Phe:
7
7
7
0
0
7
0
14
7
7
0
7
7
0
14
% F
% Gly:
0
14
0
60
7
54
7
7
0
7
0
0
14
0
14
% G
% His:
0
0
7
0
7
0
7
7
0
7
0
0
0
0
0
% H
% Ile:
0
0
7
0
7
0
0
0
7
0
7
0
7
0
40
% I
% Lys:
0
0
0
0
7
7
27
7
0
7
0
0
0
7
0
% K
% Leu:
14
7
0
7
14
7
7
0
7
7
54
14
14
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
7
0
7
14
0
% M
% Asn:
0
7
20
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
7
0
7
7
0
7
0
% P
% Gln:
0
0
7
7
0
0
0
0
0
0
7
0
0
0
7
% Q
% Arg:
0
0
7
7
54
0
20
0
0
47
0
0
0
7
7
% R
% Ser:
7
14
27
7
7
7
7
47
7
14
7
0
0
0
7
% S
% Thr:
40
0
0
0
0
7
0
0
7
0
0
7
7
7
0
% T
% Val:
7
0
0
0
0
7
14
7
0
0
0
0
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
47
0
0
0
0
7
0
% W
% Tyr:
7
14
0
7
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _